Cleveland, Ohio clinic performs US’s first face transplant

Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

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Saudis boycott Danish dairy produce

Friday, January 27, 2006

On January 26, 2006, a massive boycott of dairy produce from Arla Foods started in Saudi Arabia over what is perceived as a Danish attack on Muslim values. The Saudi ambassador to Denmark has been recalled for consultations.

The Danish/Swedish dairy company Arla is facing a massive loss after a spreading boycott of its produce in Saudi Arabia. Four Saudi retail chains have already removed Arla products from the shelves. One retail chain has placed yellow warning tape (common fare for accidents and crime scenes) over Arla products. There have been cases reported of Arla delivery trucks being attacked by stones thrown from bystanders. Marianne Castenskiold, a senior consultant for Dansk Industri, expressed a fear that the boycott will spread to other countries in the region and have detrimental effects on other Danish products. Denmark is one of the leading exporters of agriculture in northern Europe, whose economy is heavily dependent on foreign trade and investment.

The boycott has been announced at Friday prayer services in Saudi mosques since January 20, 2006, obviously helping to foment popular support of the nation’s response to Denmark’s alleged ignorance of Muslim values. On at least one occasion, a delivery truck has been greeted by thrown stones.

The boycott is a response to the publication of an article in a major Danish newspaper, Jyllands-Posten. In its September 30, 2005 issue, the paper printed 12 drawings of the Muslim prophet Muhammed, as a response to previous news reports that the publisher of a forthcoming childrens’ book about the prophet had had difficulty in finding an illustrator, due to fear of extremist reactions; drawings of the prophet are prohibited by Islamic Law (see aniconism). In an attempt to start a debate over freedom of speech in Denmark, the newspaper printed 12 drawings of the prophet. Four of these were of a satirical nature, with one showing the prophet with a turban hiding a lit bomb.

The immediate reactions to the publication of the drawings included ambassadors from 12 Muslim countries demanding that the Danish Prime Minister, Anders Fogh Rasmussen, denounce the newspaper. Rasmussen rejected this demand, stating that “Danish freedom of speech does not allow the government to control what newspapers print”. He further noted that the only possible legal action against the newspaper would be one under the charge of blasphemy.

A debate ensued over the following months about freedom of speech and its value in relation to avoiding religious taboos. In mid-December 2005, a delegation from several Danish Muslim organizations went on a tour in several Middle-Eastern and Arabic countries, reportedly to gain sympathy for their point of view. Several reports state that during the tour the difficulties faced by Muslims in Denmark were grossly overstated.

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Taiwan’s “Doritos Coolpedia” website announces top “Internet Quote”

Friday, November 2, 2007

“Among men, La-La; among horses, Red Hare” (In Chinese: ?????????) was recently elected as the “Best Internet Cool Quote”.

Laa-Laa refers to the yellow character from the Teletubbies television series, and Red Hare refers to military general Lü Bu’s horse during China’s Three Kingdoms period.

The quote was given its title after a two-week voting period, that started on October 14 until PepsiCo Taiwan & Doritos announced “Top 10 Internet Cool Quote” on October 31. Voting was on the Doritos Coolpedia website, which started on September 28.

Voting attracted more than 10,000 Internet users from 64 countries participating and electing.

Coolpedia is a portal for teens and young adults to share and contribute their creations, and interact.

At the announcement event was the famous Taiwanese band “MACHI Brothers” (MACHI). Described by Pepsico as a symbol of younger people in the presence of the e-Century in Taiwan, MACHI serves as spokespeople for the website. Members of band dressed in different “Cool Quote T-Shirts” to symbolize the “unlimited creation” of Coolpedia.

On November 1, Coolpedia launched a website for a “Cool Video Award” contest, with the slogan “No pictures, no truth!”. PepsiCo Taiwan has suggested that the site will be a major Web 2.0 site.

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Wikinews interviews India’s first female Paralympic medalist Deepa Malik

Wednesday, September 14, 2016

Wikinews on Sunday interviewed Deepa Malik, India’s first female Paralympic medalist, who won the silver medal in the Women’s Shot Put F53 event finals, at the 2016 Summer Paralympics being held in Rio de Janeiro, Brazil.

Malik lost the gold medal to Bahrain’s Fatema Nedham, who had the best throw 4.76 metres, setting a new regional record in paralympic women’s shot put.

Arriving in Rio, Malik had initial trouble due to the airline losing her luggage; it didn’t all arrive until three days later: clothes, opening ceremony outfit and equipment including competition belts.

In early August there was a possibly that Malik might lose her spot on the Indian team going to Rio, with fellow female para athlete Karam Jyoti challenging Malik’s selection and the Sport’s Authority of Indian’s selection process at the High Court of Delhi. The high court ruled against the plaintiff.

Both of these events occurred against the wider backdrop of the Paralympic Committee of India being suspended by the International Paralympic Committee. The Sports Authority of India took final authority over the Paralympic Committee of India for sending a team to Rio, with agreement from the International Paralympic Committee; this arrangement allowed India to compete under their own flag at the 2016 Summer Paralympics.

((Wikinews)) Congratulations on your result.

Deepa Malik: Thank you so much.

((WN)) Even though you are currently waiting in terms of the end result of the protest.

DM: Absolutely, but I’m happy with my performance, I’m happy that I could improve and I could prove myself, there were a lot of questions back home on my selection and on my hard work. My single-minded focus that I had put into this journey of being a Paralympian. Well, I am just so anxious about the results.

((WN)) So how much did the court case and KLM losing your luggage impact on your preparations and your result today?

DM: Yes, but I’m happy that my husband was my coach here, and, so, I had huge moral support in terms of keeping my mind and everything in peace. Most of the equipment was available in the gym, we had to alter the training a bit like the throw days couldn’t happen, so we instead exercised. No, I think that is what sports teaches you, you can’t live on excuses, I never lived on excuses.

((WN)) You work around things.

DM: Yes, that’s what we do, that’s what a sportsman is suppose to do, rise again, and then fall and rise, and run, and I did exactly that.

((WN)) What message should other Indian women take away from your participation and result in Rio?

DM: This is going to be the first female medal that India would have ever won in Paralympics and as it is I’m working aggressively towards transforming this entire concept of empowerment for the women, especially the women in disabilities in my country. So I’m really happy that this medal give my voice more value, more strength, and I’ll be able to impact even more, though on the ninth of September the Prime Minister’s jury has awarded me with the award of Women Transforming India, I’m so happy that within three days of getting that award, I have added another feather to it and proved that yes this journey of ability beyond disability. And not just disability, this is a universal message that if women put their minds to their dreams they can balance it; age, gender, disability, is all a state of mind. If you put your passion and hard work, you can get it, and in the Indian scenario were they say infrastructure is a challenge, women participation that are taboo, religiously and psychologically, disabilities taken as a curse, dependability[?] increases because of lack of infrastructure, well, time to get rid of the excuses. We have to start erasing the excuses and believe your own self and that’s the message I’m carrying with all the activities that I do whether it is car rallying, motorbiking or swimming across a river, every record or every unique activity that I’ve undertaken and just below paralysis has been aimed at changing the stereotypical image of a women and also a women in disability. ?

((WN)) Will you and your daughter both be trying to represent India at the 2020 Games in Tokyo?

DM: I’m very sure about myself, but my daughter, though, she’s a Paralympian, yes, which again was considered a huge taboo in my society that oh my god both the mother and the daughter both have a physical disability, what is going to happen to these two, but we did good and she is working as a youth council representative in the Commonwealth countries, for the Paralympics specially, and her work though her foundation called Wheeling Happiness has earned her the young leader award from the Queen of England, so I guess her focus is now shifting to more on community service and empowering others and not just herself. And she is leaving on first of October to Loughborough to do her PhD doctorate programme in disability sports psychology, I’m very sure Loughborough is going to give her a huge amount of sports [inaudible] but how much time she going to decide to devote to sports and studies is her decision entirely. That’s her dream, her journey. 

((WN)) How helpful was the Sports Authority of India in preparing and supporting your Rio ambitions??

DM: I think 100 per cent, because the biggest challenge we have back home is a customised training, or the infrastructure for that matter, so we were given the ability and the funds to train the way we wanted to train, and the funds were huge which were given to us, out accommodation, food, diet, physical therapist, psychologist, trainer, gym, everything was paid for, and customised, you want it and they give it. So I guess this was easy financially this time, because every expenses was taken care of, my husband could also take a sabbatical from his job and join my journey, and having him twenty-four seven and coaching me because he himself is an athlete, and have the best diet and counselling. I think it’s worked wonders, so I give shout out and a huge applaud.

((WN)) How important was it for you to have a carer in Rio?

DM: Yes, again we really have to appreciate the sports authority of India and also Paralympic Committee of India, which is going to start to function post-Rio in India. They were very very quick, they were very very adamant in giving the wheelchair people escorts. And I need help twenty four seven, I’m just below paralysed so it was really huge, emotionally, mentally, psychically training-wise, every way I think the situation was perfect.

((WN)) Thank you for your time.

DM: Thank you.

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Looted, possibly contaminated body parts transplanted into USA, Canadian patients

Monday, March 20, 2006

Fears of contaminated bone and skin grafts are being felt by unsuspecting patients following the revelation that funeral homes may have been looting corpses.

Janet Evans of Marion Ohio was told by her surgeon, “The bone grafts you got might have been contaminated”. She reacted with shock, “I was flabbergasted because I didn’t even know what he was talking about. I didn’t know I got a bone graft until I got this call. I just thought they put in screws and rods.”

The body of Alistair Cooke, the former host of “Masterpiece Theatre,” was supposedly looted along with more than 1,000 others, according to two law enforcement officials close to the case. The tissue taken was typically skin, bone and tendon, which was then sold for use in procedures such as dental implants and hip replacements. According to authorities, millions of dollars were made by selling the body parts to companies for use in operations done at hospitals and clinics in the United States and Canada.

A New Jersey company, Biomedical Tissue Services, has reportedly been taking body parts from funeral homes across Brooklyn, New York. According to ABC News, they set up rooms like a “surgical suite.” After they took the bones, they replaced them with PVC pipe. This was purportedly done by stealth, without approval of the deceased person or the next of kin. 1,077 bodies were involved, say prosecuters.

Investagators say a former dentist, Michael Mastromarino, is behind the operation. Biomedical was considered one of the “hottest procurement companies in the country,” raking in close to $5 million. Eventually, people became worried: “Can the donors be trusted?” A tissue processing company called LifeCell answered no, and issued a recall on all their tissue.

Cooke’s daughter, Susan Cooke Kittredge, said, “To know his bones were sold was one thing, but to see him standing truncated before me is another entirely.” Now thousands of people around the country are receiving letters warning that they should be tested for infectious diseases like HIV or hepatitis. On February 23, the Brooklyn District Attorney indicted Mastromarino and three others. They are charged with 122 felony counts, including forgery and bodysnatching.

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Penske Auto selected to buy General Motors’ Saturn unit

Friday, June 5, 2009

General Motors Corporation (GM), an American automaker which has filed for bankruptcy protection, announced on Friday that the Penske Automotive Group (PAG) was selected to purchase Saturn Corporation. The transaction should be completed in October.

The purchase includes rights to the Saturn brand, its five current models and its dealership network. Two models would be discontinued, the Sky and Astra. GM would continue building the Aura sedan, the SUV’s, Vue and Outlook for at least two more years.

Saturn has 350 dealers across the United States. The dealers employ more than 13,000 jobs and sell only the Saturn autos. Canadian Saturn dealers are not included in the deal.

According to Penske future Saturn vehicles will be fuel economy focused. An expert indicated that this would move Saturn back to its roots of a entry level car company. PAG is in talks with several international automakers to replace GM after 2011. Automotive News reports that Renault Samsung Motors of Korea is the most likely candidate.

Penske wants Jill Lajdziak, Saturn’s general manager, and Tom LaSorda, former Chrysler President to head up the company when it is independent of GM.

Serra Automotive in Grand Blanc Township, Genesee County, Michigan, is in talks to take a partial ownership in a new Saturn lead by Penske.

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U.S. manufacturer General Motors seeks bankruptcy protection

Monday, June 1, 2009

United States automobile manufacturing firm General Motors filed for bankruptcy and Chapter 11 protection from its creditors at 12:00 UTC Monday, in a Manhattan, New York federal bankruptcy court. This was the largest bankruptcy filing for a U.S. manufacturing company, and with declared assets of $82.29 billion and a debt of $172.81 billion, and the fourth largest bankruptcy filing in recent U.S. history — after the bankruptcies of {{w|Lehman Brothers|| ($691.06 billion), Washington Mutual ($327.91 billion), and WorldCom ($103.91 billion).

The filing, expected to be the first of many, was for a New York GM affiliate, Chevrolet-Saturn of Harlem Incorporated. Numbered 09-50026, it named GM as a debtor in possession, and was filed before judge Robert Gerber.

GM is to be represented throughout the filing process by Weil Gotshal & Manges, a New York law firm specializing in bankruptcy.

The chief restructuring officer, named in the filing, is to be Al Koch, a managing director at AlixPartners LLP in New York, who will report directly to Fritz Henderson, the Chief Executive Officer of General Motors.

In its bankruptcy petition, GM listed its primary creditors as:

Name Amount owed (USD millions)
Wilmington Trust 22,000
United Auto Workers union (UAW) 20,560
Deutsche Bank 4,440

The amount owed to UAW excludes “approximately $9.4 billion corresponding to the GM Internal VEBA”. USD22,760 millions are owed to bondholders.

Analysts have observed that the effect of the bankruptcy filing on the U.S. economy is not expected to be as major as it once would have been. One such voice, Mark Zandy, an economist at Moody’s Economy.com, commented that “Bankruptcy now is irrelevant in terms of the economic consequence of what’s happening to GM.” Such analysts believe that the economic impact of GM’s problems has already been felt, with its effects on parts suppliers and employment. They also believe that GM’s programme of accelerated payments, and its participation in a U.S. Treasury program to ensure prompt payments to parts manufacturers, will have cushioned the effect of the bankruptcy itself.

Speaking on Bloomberg Radio, David Cole, chairman of the Center for Automotive Research in Ann Arbor, stated that the fragility of the parts suppliers, the loss of whom would threaten the entire automobile manufacturing industry, was of more immediate concern than the GM bankruptcy.

Also filing for chapter 11 protection today were Saturn LLC and Saturn Distribution Corporation, subsidiary companies of General Motors.

As a consequence of the bankruptcy, General Motors Corporation (GM.N) was removed from the Dow Jones Industrial Average, and was replaced by Cisco Systems (CSCO.O), these changes scheduled by Dow Jones & Company to take effect from the opening of trading on June 8.

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Scottish archaeology student discovers 5,000 year old chewing gum in Finland

Thursday, August 23, 2007

An archaeology student from Scotland has discovered a 5,000 year old piece of chewing gum on a dig in Finland.

Sarah Pickin, a 23-year-old part-time barmaid studying archaeology with Derby University, discovered the gum during a dig in the north-west of the country. The gum is a lump of birch bark tar, and still has visible tooth marks. It has been sent away for analysis, and radio carbon dating is predicted to show the gum to be 5,000 years old.

Ms Pickin said of her discovery “I had heard of ancient chewing gum being found before on previous European digs so when I found it in the trench, it was the first thing that crossed my mind.

“However, it looks just like a dirty piece of modern chewing gum with no smell or taste and I was also worried it could have been a bit of fossilised poo, so I asked a few of the other students to make sure.

“Thankfully they agreed that it was birch-bark gum and it’s now away to be carbon dated and have the teeth marks analysed before it goes on display.”

It will be displayed in Finland’s Kierikki centre, which is devoted to finds from the area. Sarah Pickin also discovered a piece of an amber ring, a slate arrowhead and a hair needle. All the finds date to the Neolithic period.

It is believed the gum was chewed as an aid against gum disease, as it contains antiseptics.

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Palestinians arrested in West Bank raids

Saturday, August 13, 2005

During overnight raids, Israeli soldiers arrested 10 people, allegedly members of Islamic Jihad, a Palestinian militant group. The raids were conducted during two operations near the towns of Jenin and Nablus. An M-16 rifle was also discovered during the raid near Jenin.

Meanwhile, Hamas, a group friendly to Islamic Jihad, made a rare public appearance 2 days before the Israeli pull-out of settlers and troops from The Gaza Strip. They defied the Palestinian Authority by draping themselves in the colours of the group. On Friday, Palestinian Authority officials said only the Palestinian banner of red, black, green and white should be used to celebrate the withdrawal of Israel from Palestinian territory.

Hamas are planning to run in the parliamentary elections to be held in January, next year.

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