Thursday, December 18, 2008

A team of eight transplant surgeons in Cleveland Clinic in Ohio, USA, led by reconstructive surgeon Dr. Maria Siemionow, age 58, have successfully performed the first almost total face transplant in the US, and the fourth globally, on a woman so horribly disfigured due to trauma, that cost her an eye. Two weeks ago Dr. Siemionow, in a 23-hour marathon surgery, replaced 80 percent of her face, by transplanting or grafting bone, nerve, blood vessels, muscles and skin harvested from a female donor’s cadaver.

The Clinic surgeons, in Wednesday’s news conference, described the details of the transplant but upon request, the team did not publish her name, age and cause of injury nor the donor’s identity. The patient’s family desired the reason for her transplant to remain confidential. The Los Angeles Times reported that the patient “had no upper jaw, nose, cheeks or lower eyelids and was unable to eat, talk, smile, smell or breathe on her own.” The clinic’s dermatology and plastic surgery chair, Francis Papay, described the nine hours phase of the procedure: “We transferred the skin, all the facial muscles in the upper face and mid-face, the upper lip, all of the nose, most of the sinuses around the nose, the upper jaw including the teeth, the facial nerve.” Thereafter, another team spent three hours sewing the woman’s blood vessels to that of the donor’s face to restore blood circulation, making the graft a success.

The New York Times reported that “three partial face transplants have been performed since 2005, two in France and one in China, all using facial tissue from a dead donor with permission from their families.” “Only the forehead, upper eyelids, lower lip, lower teeth and jaw are hers, the rest of her face comes from a cadaver; she could not eat on her own or breathe without a hole in her windpipe. About 77 square inches of tissue were transplanted from the donor,” it further described the details of the medical marvel. The patient, however, must take lifetime immunosuppressive drugs, also called antirejection drugs, which do not guarantee success. The transplant team said that in case of failure, it would replace the part with a skin graft taken from her own body.

Dr. Bohdan Pomahac, a Brigham and Women’s Hospital surgeon praised the recent medical development. “There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Leading bioethicist Arthur Caplan of the University of Pennsylvania withheld judgment on the Cleveland transplant amid grave concerns on the post-operation results. “The biggest ethical problem is dealing with failure — if your face rejects. It would be a living hell. If your face is falling off and you can’t eat and you can’t breathe and you’re suffering in a terrible manner that can’t be reversed, you need to put on the table assistance in dying. There are patients who can benefit tremendously from this. It’s great that it happened,” he said.

Dr Alex Clarke, of the Royal Free Hospital had praised the Clinic for its contribution to medicine. “It is a real step forward for people who have severe disfigurement and this operation has been done by a team who have really prepared and worked towards this for a number of years. These transplants have proven that the technical difficulties can be overcome and psychologically the patients are doing well. They have all have reacted positively and have begun to do things they were not able to before. All the things people thought were barriers to this kind of operations have been overcome,” she said.

The first partial face transplant surgery on a living human was performed on Isabelle Dinoire on November 27 2005, when she was 38, by Professor Bernard Devauchelle, assisted by Professor Jean-Michel Dubernard in Amiens, France. Her Labrador dog mauled her in May 2005. A triangle of face tissue including the nose and mouth was taken from a brain-dead female donor and grafted onto the patient. Scientists elsewhere have performed scalp and ear transplants. However, the claim is the first for a mouth and nose transplant. Experts say the mouth and nose are the most difficult parts of the face to transplant.

In 2004, the same Cleveland Clinic, became the first institution to approve this surgery and test it on cadavers. In October 2006, surgeon Peter Butler at London‘s Royal Free Hospital in the UK was given permission by the NHS ethics board to carry out a full face transplant. His team will select four adult patients (children cannot be selected due to concerns over consent), with operations being carried out at six month intervals. In March 2008, the treatment of 30-year-old neurofibromatosis victim Pascal Coler of France ended after having received what his doctors call the worlds first successful full face transplant.

Ethical concerns, psychological impact, problems relating to immunosuppression and consequences of technical failure have prevented teams from performing face transplant operations in the past, even though it has been technically possible to carry out such procedures for years.

Mr Iain Hutchison, of Barts and the London Hospital, warned of several problems with face transplants, such as blood vessels in the donated tissue clotting and immunosuppressants failing or increasing the patient’s risk of cancer. He also pointed out ethical issues with the fact that the procedure requires a “beating heart donor”. The transplant is carried out while the donor is brain dead, but still alive by use of a ventilator.

According to Stephen Wigmore, chair of British Transplantation Society’s ethics committee, it is unknown to what extent facial expressions will function in the long term. He said that it is not certain whether a patient could be left worse off in the case of a face transplant failing.

Mr Michael Earley, a member of the Royal College of Surgeon‘s facial transplantation working party, commented that if successful, the transplant would be “a major breakthrough in facial reconstruction” and “a major step forward for the facially disfigured.”

In Wednesday’s conference, Siemionow said “we know that there are so many patients there in their homes where they are hiding from society because they are afraid to walk to the grocery stores, they are afraid to go the the street.” “Our patient was called names and was humiliated. We very much hope that for this very special group of patients there is a hope that someday they will be able to go comfortably from their houses and enjoy the things we take for granted,” she added.

In response to the medical breakthrough, a British medical group led by Royal Free Hospital’s lead surgeon Dr Peter Butler, said they will finish the world’s first full face transplant within a year. “We hope to make an announcement about a full-face operation in the next 12 months. This latest operation shows how facial transplantation can help a particular group of the most severely facially injured people. These are people who would otherwise live a terrible twilight life, shut away from public gaze,” he said.

Wednesday, May 3, 2006

On Friday, April 28, Wikinews interviewed Ethan Zuckerman, the founder of Geekcorps, a non-profit organization that sending people with technical skills to developing countries for development projects. Ethan has also founded Global Voices Online and helped found Tripod.com, the free web-hosting company now owned by Lycos. He serves a fellow at the Berkman Center for Internet and Society. Tripod.

The interview was held publicly in a dedicated IRC channel.

• What insipred you to get behind Geekcorps, and has there been a big Geekcorps mission, yet?

I got interested in Geekcorps because I’d lived in Ghana as a student in 1993 and 1994While over there, I was amazed at just how little internet connectivity was availableI did a bit of volunteer work helping wire an environmental organization, but basically the only people who had regular net access were US embassy employees.So I was fascinated to learn that my friends in Ghana were getting online in the late 1990s, and I wondered whether anyone would start building net-based businesses, as people were doing in the USMy wife and I went back to Ghana to visit friends and found that there was a huge deal of enthusiasm about the web and the potential it represented, but almost no expertisepeople were really desperate to learn, but very few people were able to teach at the same time, I was ready to step down from Tripod, and I knew a lot of burned out geeksI started wondering whether some of my friends would be interested in sharing their skills in the developing world and whether that would be a useful thing to dolots of international development folks seemed to think it was a good cause, so I started working on it fulltime.We ended up sending about 100 people overseas over the four years I was involved with the projectwe usually sent about 6-8 to a country at a time, working with a variety of businesses, NGOs and government agencies biggest projects were in Ghana, Mali, Mongolia, Senegal.

• With Geekcorps you pushed the idea that newly tech-savvy citizens of developing countries could start online businesses to do digital work for the developed world. But from an American perspective, that’s outsourcing, the bane of US workers. How do you justify working towards a goal that might cost Americans their jobs?

Basically, I’m concerned about the ability of people all over the world to make a good living, send their children to school, build nice houses, have enough food and clean water, etc there’s clearly something of a tradeoff offered by all sorts of globalization – as millions of Chinese are lifted out of rural povery, industrial manufacturing jobs in the US disappear but the US has a pretty good history of innovating and creating new jobs in fields that require a lot of intellectual endeavor the US continues to found interesting software companies, pioneer new net services and generally do a lot of the interesting development on the cutting edge of tech I think a lot of routine coding jobs are up for outsourcing, but I don’t think that people who design software – or who manage the outsourcing and software development process – are going away any time soon it’s very hard to outsource creative activities – it’s somewhat easier to outsource repetitive processes.I think we need to worry less about individual job loss and more about the ability to continue creating new projects. at the same time, I’m very excited to see companies in the developing world moving up the value chain as well, starting to innovate and create new projects as well…

• Lately you’ve been involved with projects including Global Voices and Worldchanging. Where and how do the two dovetail, and where and how do they differ? What are the strengths of each?

They’re very different projects and communities, WC is a magazine -it’s a chance for a small group of smart people to write original content on green issues it’s a lot less global than GV – perhaps overly focused on the US and Europe – and has a tight subject focus GV is an edited aggregator People are not so much writing original, opinionated content on GV as they are linking to other content indeed, we ask people to try very hard not to be especially opinionated on GV. Not NPOV, but a similar perspective – you point, you don’t advocate<ethanz> also GVO is huge – 10 regional editors, about 60 regular contributors, a network of about a thousand blogs we regularly link to the community has a very different feeling – much more international, more 24/7. both are fascinating projects, successes in their own ways, but quite different on the tech issues, a little – in both cases, we’re taking very simple weblog tools and asking them to support very large communities. And a little bit on the issue of how they interface with mainstream media in both cases, we’re interested in amplifying memes and getting them picked up by popular press as well as on the web.

• Isn’t that a contradiction? you’re asking people to be “less” opinionated, but not asking them to be unopinionated?

Blogs are essentially about opinion, asking for NPOV in the blog space misses the point – we want to know what opinions people in Syria have but we want our middle east editor to try to fairly represent the different opinions taking place in that space that said, he’s got an opinion as well so asking for NPOV isn’t the right thing to do – asking him to point to a diversity of opinions is, in our case

Geekcorps can be found online at www.geekcorps.org and Global Voices Online is at www.globalvoicesonline.org.

Thursday, September 13, 2007

Having worked as an aide, advisor, and Executive Assistant to municipal and provincial politicians, Sheila White is running for the Ontario New Democratic Party in the Ontario provincial election, in the Scarborough-Rouge River riding. Wikinews’ Nick Moreau interviewed her regarding her values, her experience, and her campaign.

Stay tuned for further interviews; every candidate from every party is eligible, and will be contacted. Expect interviews from Liberals, Progressive Conservatives, New Democratic Party members, Ontario Greens, as well as members from the Family Coalition, Freedom, Communist, Libertarian, and Confederation of Regions parties, as well as independents.

Wednesday, April 18, 2007

In France, voting has traditionally been a low-tech experience: voters isolate themselves in a booth, put a pre-printed sheet of paper indicating their candidate of choice into an envelope. After officials verify the voter’s identity, the voter drops the envelope into the ballot box and signs the voting roll. French electoral law rather strictly codifies the proceedings. Since 1988, ballot boxes must be transparent so that voters and observers can witness that no envelopes are present at the start of the vote and that no envelopes are added except those of the duly counted and authorized voters. Candidates can send representatives to witness every part of the process. In the evening, votes are counted by volunteers under heavy supervision, following specific procedures.

In the past, voting machines, though authorized by law, were scarce. But this year, during presidential elections (the first round was April 22, the second is on May 6), the country is shaken by controversy about the machines intended to count about 1.5 million votes.

As in the United States, there is a group of academic computer scientists that oppose voting machines. They argue that voting machines replace a public, easily understandable counting process, where large-scale fraud would entail large-scale corruption, by an opaque process where votes are counted by machines that voters have to blindly trust. Voting machines have to be approved by the Ministry of the Interior, but this approval is based on confidential reports by private companies. Opponents to the machines point out that the Ministry was long held by Nicolas Sarkozy, who happens to be the leading candidate. Opponents also list a number of weaknesses and discrepancies that have occurred in other countries using voting machines.

All main political parties except UMP, Mr Sarkozy’s ruling party, oppose the voting machines. Some citizens have filed for court injunctions against the voting machines. Opponents have given detailed instructions that voting witnesses should check whether the machines correspond exactly to an approved type, including software versions, and fulfill all legal conditions. In a sign of the frenzy over the issue, on April 12 the Ministry of the Interior issued a last-minute authorization for a specific model (hardware, firmware). The stakes are high: votes on unapproved machines should be canceled by the Constitutional Council for the official count.

The opposition has crystallized on the Paris suburb of Issy-les-Moulineaux. Issy’s mayor, André Santini is a well-known technophile; his city organizes a “World E-Gov Forum”. Here too, last minute fixes are at work. The machines delivered to the city are of a yet-to-be-approved type. The manufacturer, the American company ES&S voting systems, is now delivering older 2005 machines. Le Monde reports that other municipalities have already replaced their recent machines by an older, approved, model.

Proponents of the machines, such as the French company France Élection, claim they are being defamed and dispute the competence of their critics. Elected officials supporting the machines claim the machines save on paper, time, and the need to find volunteers to count votes.

Monday, December 2, 2013

Police in the West Midlands in England today said nearly 200 kilograms worth of drugs with value possibly as great as £30 million (about US$49 million or €36 million) has been seized from a unit in the town of Brownhills. In what an officer described as “one of the largest [seizures] in the force’s 39 year history”, West Midlands Police reported recovering six big cellophane-wrapped cardboard boxes containing cannabis, cocaine, and MDMA (“ecstasy”) in a police raid operation on the Maybrook Industrial Estate in the town on Wednesday.

The seized boxes, which had been loaded onto five freight pallets, contained 120 one-kilogram bags of cannabis, 50 one-kilogram bags of MDMA, and five one-kilogram bricks of cocaine. In a press release, West Midlands Police described what happened after officers found the drugs as they were being unloaded in the operation. “When officers opened the boxes they discovered a deep layer of protective foam chips beneath which the drugs were carefully layered”, the force said. “All the drugs were wrapped in thick plastic bags taped closed with the cannabis vacuum packed to prevent its distinctive pungent aroma from drawing unwanted attention.” Police moved the drugs via forklift truck to a flatbed lorry to remove them.

Detective Sergeant Carl Russell of West Midlands Police’s Force CID said the seizure was the largest he had ever made in the 24 years he has been in West Midlands Police and one of the biggest seizures the force has made since its formation in 1974. “The impact this seizure will have on drug dealing in the region and the UK as a whole cannot be underestimated”, he said. “The drugs had almost certainly been packed to order ready for shipping within Britain but possibly even further afield. Our operation will have a national effect and we are working closely with a range of law enforcement agencies to identify those involved in this crime at whatever level.”

Expert testing on the drugs is ongoing. Estimates described as “conservative” suggest the value of the drugs amounts to £10 million (about US$16.4 million or €12 million), although they could be worth as much as £30 million, subject to purity tests, police said.

Police arrested three men at the unit on suspicion of supplying a controlled drug. The men, a 50-year-old from Brownhills, a 51-year-old from the Norton area of Stoke-on-Trent in Staffordshire, and one aged 53 from Brownhills, have been released on bail as police investigations to “hunt those responsible” continue. West Midlands Police told Wikinews no person has yet been charged in connection with the seizure. Supplying a controlled drug is an imprisonable offence in England, although length of jail sentences vary according to the class and quantity of drugs and the significance of offenders’ roles in committing the crime.

Friday, May 8, 2009

Thomas Sam, 42, and his wife Manju Sam, 36, from Sydney, Australia, are undergoing trial for manslaughter by gross negligence for the death of their nine-month-old child, Gloria. She died from infection caused by severe eczema after they shunned effective conventional medical treatments for homeopathy, a form of alternative medicine that has been described as pseudoscience. Articles in peer-reviewed academic journals including Social Science & Medicine have characterized homeopathy as a form of quackery.

Gloria developed severe eczema at the age of four months and the parents were advised to send the child to a skin specialist. Thomas Sam, a practising homeopath, instead decided to treat his daughter himself. His daughter’s condition deteriorated, to the point that the baby spent all her energy battling the infections caused by the constant breaking of the skin, leading to severe malnutrition and, eventually, her death. By the end, Gloria’s eczema was so severe that her skin broke every time her parents changed her clothes or nappy, and in the words of the Crown prosecutor, Mark Tedeschi, QC, “Gloria spent a lot of the last five months of her life crying, irritable, scratching and the only thing that gave her solace was to suck on her mother’s breast.” Gloria also became unable to move her legs.

Mr. Tedeschi also told the court that, over the last five months of her life, “Gloria’s eczema played a devastating role in her overall health and it is asserted by the Crown that both her parents knew this and discussed it with each other.” However, despite their child’s severe illness, and her lack of improvement, the Sams continued to shun conventional medical treatment, instead seeking help from other homeopaths and naturopaths. Gloria temporarily improved during the rare times they used conventional treatments, but they soon dropped them in favour of homeopathy, and she consistently worsened.

Allegedly, Thomas’ sister pleaded with him to send Gloria to a conventional medical doctor, but he replied “I am not able to do that”. The parents are also accused of putting their social life ahead of their child, taking her on a trip to India and leaving her to servants while embarking on a busy social schedule, and giving her homeopathic drops instead of using the prescription creams they had been given.

Gloria was finally taken to the emergency department shortly before her death. By this time, “her skin was weeping, her body malnourished and her corneas melting”, according to the Sydney Morning Herald.

Speaking in the parents’ defense, Tom Molomby, SC, said that, as the parents came from India, where homeopathy is in common use, they should be declared not guilty due to cultural differences.

Homeopathy is a form of alternative medicine which treats patients with massively diluted forms of substances that, if given to a healthy person undiluted, would cause symptoms similar to the disease. Typical treatments take the dilutions, with ritualised shaking between each step of the dilution, past the level where any molecules of the original substance are likely to remain; for homeopathic treatments to work, basic well-understood concepts in chemistry and physics would have to be wrong. There is no evidence that homeopathy is more effective than placebo for any condition.

Tuesday, August 14, 2007

The closure of a mathematics summer camp in ?irince, ?zmir, Turkey by Turkish authorities has drawn scorn from scientists around the world.

Professor Alexandre Borovik, who organized some of the opposition, said “We are shocked to learn that the Summer School of Mathematics initiated by Professor Ali Nesin was shut down by local authorities. We found it surprising that such an esteemed mathematician such as Professor Nesin needs a specific permit each time he wants to teach math, as we saw that one of the reasons for shutting the camp down was the lack of such a permit, especially considering how this contradicts the fact that the summer schools organized every year by Professor Nesin are sponsored by The Scientific and Technological Research Council of Turkey (TÜB?TAK), Turkish Mathematics Association and many respected Turkish universities.”

The school was reopened on August 10, 2007; however, Ali Nesin still faces charges under Turkish criminal code article TCK 263, which reads “Persons who open or run illegal educational institutions can be jailed from 3 months to 1 year.”

Ali Nesin is the son of the famous Turkish humorist Aziz Nesin.